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Green Tea Protects Cells From Cancer-Causing DNA Damage

Study description: Researchers exposed human lymphoid cells to a substance called (+/-)-anti-benzo[a]pyrene diol epoxide (BPDE), which is known to induce the kind of DNA damage that can lead to lung cancer. Some of the human lung cells were from people with lung cancer, some from people without cancer. 

Type of study: "Test-tube"

What happened: When green tea extract was added to cells from either group prior to exposure to BPDE, there was a "notable reduction" in DNA damage. 

Researchers' conclusion: These findings "demonstrated the chemopreventive effects of green tea extract" on deliberately-induced DNA damage that might otherwise lead to cancer.

Citation: Zhang H, Spitz MR, Tomlinson GE, et al. Modification of lung cancer susceptibility by green tea extract as measured by the comet assay. Cancer Detection and Prevention 2002;26(6):411-8. (Click here to read PubMed study abstract.)


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