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Tea Extracts Protect Against Radiation-Induced Skin Damage

Background: Skin toxicity is a common side effect of radiation for solid tumors and, besides damaged skin, it can lead to gaps in cancer treatment while the skin heals. Researchers from UCLA and the University of Freiburg, Germany wanted to find out if green and black tea extracts, with their anti-inflammatory properties, could protect against skin toxicity and reduce its duration.

Participants: 60 patients with cancer of the head and neck or pelvic region

Type of study: Prospective experimental

Study Methods: The volunteers were given topical skin treatments of green or black tea extracts before their radiation treatments.

What happened: The tea extracts, which in “test tube” studies reduced the release of pro-inflammatory cytokines, decreased the duration of skin toxicity after radiation by 5-10 days in the cancer patients. These effects were seen with both green and black tea extracts, although green tea extract was more effective.

Researchers' conclusion: "Tea extracts are an efficient, broadly available treatment option for patients suffering from acute radiation-induced skin toxicity."

Citation: Pajonk F, Riedisser A, Henke M, et al. The effects of tea extracts on proinflammatory signaling. BMC Med 2006;4:28. (Click here to read PubMed study abstract.)


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