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Green Tea and Liver Disease

The liver is a vital organ that performs a multitude of important bodily functions. These include the breakdown and detoxification of toxins (including alcohol, drugs and environmental pollutants), the metabolism of protein, fats and carbohydrates, the storage of vitamins and minerals, the regulation of blood clotting, the production of proteins and enzymes and the maintenance of hormone balance. The liver also filters bacteria out of the blood and makes bile, which is necessary for proper digestion. Clearly, keeping the liver strong and well-functioning is essential to good health – and it appears that green tea may be able to help.

Alcohol is one of the biggest enemies of the liver. The chronic intake of more alcohol than the liver can process causes fatty liver, alcoholic hepatitis or cirrhosis and may even result in death. To find out if green tea polyphenols can prevent at least some alcohol-related damage to the liver, Chinese researchers infused laboratory rats with alcohol for 12 weeks; some of the rats were also given green tea polyphenols.1 At the end of the study period, the rats that received the polyphenols had less liver damage than those receiving alcohol alone. Specifically, there was a lower level of fat and collagen deposition in the liver and a reduced rate of liver cell death.

But does green tea have the same effect on the human liver? A survey of 1,371 Japanese men over the age of 40 found that those who drank large amounts of green tea, especially more than 10 cups a day, had lower blood levels of certain markers of liver damage (AST, alanine transferase and ferritin).2 And a 2008 review of ten human studies on green tea consumption and liver disease found that eight of these studies showed a significantly protective role of green tea against various liver diseases, including cancer, cirrhosis and fatty liver disease.3 The remaining two studies also showed a protective effect, but to a lesser degree. The researchers concluded that, “an increased consumption of green tea may reduce the risk of liver disease.”

1Zhang XG, Xu P, Liu Q, et al. Effect of tea polyphenol on cytokine gene expression in rats with alcoholic liver disease. Hepatobilliary Pancreat Dis Int 2006;5(2):268-72.
2
Imai K, Nakachi K. Cross sectional study of effects of drinking green tea on cardiovascular and liver diseases. BMJ 1995;310(6981):693-96.
3
Jin X, Zheng RH, Li YM. Green tea consumption and liver disease: a systematic review. Liver Int 2008;28(7):990-96.


Nadine Taylor, M.S., R.D. presents GreenTeaLibrary.com, the most comprehensive collection of scientific information describing the health benefits of green tea. 


 

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