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Green Tea and Tissue Preservation

We’ve all heard about cryopreservation – preserving living tissue by freezing it and storing it at super low temperatures. It works by stopping all biological activity, including the biochemical reactions that would normally lead to cell death. But the process is far from perfect. Cell injury or death can and does occur, especially during the initial freezing and warming stages. But now, thanks to green tea, there may be a much gentler approach.

A researcher at Kyoto University in Japan has demonstrated that several kinds of tissues can actually be preserved at room temperature when immersed in a solution containing green tea polyphenols.1 He found that tissues such as blood vessels, cartilage, islet cells (the cells responsible for making insulin), and corneas can be preserved for several months at room temperature as long as they are immersed in this green tea solution.

Another study found that rat aortas preserved for a month in a solution containing green tea polyphenols kept their mechanical strength and were not rejected when transplanted.2 A third study found that nerve segments stored in a polyphenol solution reduced transplant rejections in rats.3

Considering green tea’s potent antioxidant, anti-inflammatory and antibacterial properties, these results may not be too surprising. Today, green tea extract is widely used as a preservative in foods and cosmetics, is ten times more effective than vitamin E, and is 2.5 times more potent than vitamin C at preventing the spoilage of fats and oils.

Although scientists still aren’t sure exactly how green tea polyphenols preserve living tissue, the fact that it can do so without apparent side effects heralds an exciting new discovery in the field of tissue transplantation.

1Hyon SH. A non-frozen living tissue bank for allotransplantation using green tea polyphenols. Yonsei Med J 2004;45(6):1025-34.) 
2Hyon SH, Kim DH, Cui W, et al. Preservation of rat aortic tissue transplant with green tea polyphenols. Cell Transplant 2006;15(10):881-883.
3 Ikeguchi R, Kakinoki R, Okamoto T, et al. Successful storage of peripheral nerve before transplantation using green tea polyphenol: an experimental study in rats. Exp Neurol 2003;184(2):688-96.


Nadine Taylor, M.S., R.D. presents GreenTeaLibrary.com, the most comprehensive collection of scientific information describing the health benefits of green tea. 


 

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